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reaction mass of 1,3-dioxan-5-ol and 1,3-dioxolan-4-ylmethanol

CAS -
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cyclic acetal used as a solvent and fragrance fixative, with low acute toxicity and good tolerability on skin.

This reaction mass of 1,3-dioxan-5-ol and 1,3-dioxolan-4-ylmethanol consists of cyclic acetals used as green solvents and fragrance fixatives. They are not classified as skin sensitizers under EU CLP. No specific EU CosIng restriction applies. The dioxolane and dioxane rings can hydrolyze under acidic skin conditions, releasing small amounts of formaldehyde-equivalent species.

Skin benefits

  • Solvent for cosmetic formulations
  • Fragrance fixative

Known concerns

  • Can hydrolyze to release minor amounts of aldehyde species
  • Generally low toxicity but limited long-term dermal data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.