Reaction products of diisopropanolamine with formaldehyde (1:4)
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A formaldehyde-amine condensation product used in industrial applications, acting as a formaldehyde releaser with sensitisation potential.
This compound is a Mannich-base formaldehyde releaser, structurally similar to other cosmetic preservatives like DMDM hydantoin. It releases formaldehyde at room temperature and in solution. Formaldehyde releasers are restricted in the EU under Annex V (preservatives) or Annex III, and must be declared on the ingredient list. The 1:4 ratio of DIPA to formaldehyde suggests significant formaldehyde release potential.
Skin benefits
- Industrial biocide and preservative function
Known concerns
- Formaldehyde releaser - contact allergen
- Skin sensitiser
- EU preservative/formaldehyde releaser regulation applies
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.