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Skin Conditioning

RETINOYL TETRAPEPTIDE-43 AMIDE

58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A hybrid retinoid–peptide compound joining retinoic acid with a tetrapeptide — promises anti-aging activity with reduced irritation. Retinoid-class avoid-in-pregnancy caution still applies.

Function

SKIN CONDITIONING

Skin benefits

  • Retinoid-peptide hybrid with anti-aging signal
  • Possibly milder than free retinoic acid
  • Defined synthetic identity

Known concerns

  • Retinoid moiety — potential photo-sensitivity and irritation
  • Pregnancy/breastfeeding caution — class-level avoid
  • Limited independent safety data on this exact hybrid

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.