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Skin Conditioning

RH-POLYPEPTIDE-15

CAS 124861-55-8
74

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made copy of human TIMP-2 — a protein that balances skin matrix remodeling. Used at minute cosmetic doses; cautious tier reflects its underlying biological signaling activity.

Function

SKIN CONDITIONING

Skin benefits

  • Recombinant TIMP-2 analog supports matrix remodeling balance
  • High-purity E. coli production
  • Used at very low cosmetic doses

Known concerns

  • TIMP-2 modulates protease activity — biological potency warrants caution
  • EU Annex II/416 references suggest restricted use
  • Limited public cosmetic safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.