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Skin Conditioning

RH-POLYPEPTIDE-19

CAS 93585-89-8 / 105186-99-0 Updated
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A lab-made copy of human Transforming Growth Factor Alpha — an EGF-family signaling protein. Cautious tier because of growth-factor activity, despite minute cosmetic dosing.

Function

SKIN PROTECTING

Skin benefits

  • Recombinant TGF-alpha analog supports skin renewal
  • High-purity E. coli production
  • Used at very low cosmetic doses

Known concerns

  • TGF-alpha is an EGF-family growth factor — caution warranted
  • EU Annex II/416 references suggest restricted use
  • Theoretical concern for stimulating dormant lesions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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(ARTEMISIA SIEVERSIANA/DIMOCARPUS LONGANA) FLOWER/LEAF/STEM EXTRACT
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(ASPARAGUS COCHINCHINENSIS/LIRIOPE MUSCARI/REHMANNIA CHINENSIS) ROOT EXTRACT
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1,3-Dihydroxy-2-propanone
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ABIES ALBA WOOD EXTRACT
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.