Skip to content

Skin Conditioning

RH-POLYPEPTIDE-19

CAS 93585-89-8 / 105186-99-0
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made copy of human Transforming Growth Factor Alpha — an EGF-family signaling protein. Cautious tier because of growth-factor activity, despite minute cosmetic dosing.

Function

SKIN PROTECTING

Skin benefits

  • Recombinant TGF-alpha analog supports skin renewal
  • High-purity E. coli production
  • Used at very low cosmetic doses

Known concerns

  • TGF-alpha is an EGF-family growth factor — caution warranted
  • EU Annex II/416 references suggest restricted use
  • Theoretical concern for stimulating dormant lesions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

70
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Skin Conditioning
 70
(ARNICA MONTANA/CALENDULA OFFICINALIS/MATRICARIA CHAMOMILLA) FLOWER EXTRACT
Skin Conditioning
 70
(ARTEMISIA SIEVERSIANA/DIMOCARPUS LONGANA) FLOWER/LEAF/STEM EXTRACT
Skin Conditioning
 70
(ASPARAGUS COCHINCHINENSIS/LIRIOPE MUSCARI/REHMANNIA CHINENSIS) ROOT EXTRACT
Skin Conditioning
 70
(CNIDIUM OFFICINALE/COPTIS CHINENSIS/GLYCYRRHIZA URALENSIS) ROOT EXTRACT
Skin Conditioning
 70
(VETIVERIA ZIZANOIDES ROOT/PUERARIA THUNBERGIANA FLOWER/LEAF/STEM) WATER
Skin Conditioning
 70
1,3-Dihydroxy-2-propanone
Skin Conditioning
 70
ABIES ALBA WOOD EXTRACT
Skin Conditioning

Check your shelf

Find RH-POLYPEPTIDE-19 in your products.

Scan any cosmetic product with LuxSense to see if it contains RH-POLYPEPTIDE-19 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.