Skip to content

Skin Conditioning

RH-POLYPEPTIDE-3

CAS 126469-10-1
62

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A recombinant human epidermal growth factor used in cosmetics for renewal claims. Effective signaling but raises long-term safety questions, especially around growth modulation.

Function

SKIN CONDITIONING

Skin benefits

  • Recombinant human EGF for cell signaling
  • Marketed for skin renewal
  • Used at extremely low %

Known concerns

  • Growth-factor activity raises long-term safety questions
  • Limited independent peer-reviewed cosmetic data
  • Stability sensitive, often co-formulated with preservatives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

62
4-ISOBUTYLRESORCINOL
Skin Conditioning
 62
ABRONIA VILLOSA LEAF EXTRACT
Skin Conditioning
 62
ACETYL SH-OLIGOPEPTIDE-26 SH-OLIGOPEPTIDE-27 SP
Skin Conditioning
 62
ACETYL SH-OLIGOPEPTIDE-77 AMIDE
Skin Conditioning
 62
ACINETOBACTER FERMENT EXTRACT
Skin Conditioning
 62
ACORUS GRAMINEUS RHIZOME EXTRACT
Skin Conditioning
 62
ALBIZIA ADIANTHIFOLIA LEAF EXTRACT
Skin Conditioning
 62
ALLOFERON-1
Skin Conditioning

Check your shelf

Find RH-POLYPEPTIDE-3 in your products.

Scan any cosmetic product with LuxSense to see if it contains RH-POLYPEPTIDE-3 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.