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Skin Conditioning

RH-POLYPEPTIDE-4

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made copy of human Stem Cell Factor, which signals melanocytes and stem cells. Cautious tier because of theoretical concerns about stimulating dormant pigmented lesions.

Function

SKIN CONDITIONING

Skin benefits

  • Recombinant Stem Cell Factor analog supports skin conditioning
  • High-purity E. coli production
  • Used at very low cosmetic doses

Known concerns

  • SCF stimulates melanocyte and stem cell proliferation — caution warranted
  • Theoretical concern for stimulating dormant pigmented lesions
  • EU Annex II/416 references suggest restricted use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.