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RIBOFLAVIN TETRABUTYRATE

CAS 752-56-7
94

Safety score · 0–100

Excellent

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A vitamin B2 (riboflavin) derivative with antioxidant properties.

Riboflavin tetrabutyrate (riboflavin tetrabutanoate, CAS 752-56-7) is a tetraester of riboflavin (vitamin B2) with butyric acid, creating a lipophilic vitamin derivative that is more compatible with oil-phase cosmetic formulations than free riboflavin. Riboflavin is an essential vitamin with well-documented safety in both dietary and topical applications. As a cosmetic ingredient, it functions as a skin conditioning agent and antioxidant. Under EU Regulation (EC) No 1223/2009, riboflavin and its derivatives are permitted without restriction. The butyrate esterification improves oil solubility while the riboflavin core retains its characteristic yellow color and antioxidant properties.

Skin benefits

  • Antioxidant protection
  • Skin conditioning
  • Vitamin B2 benefit for skin metabolism

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.