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ROSE KETONE-3

CAS 57378-68-4
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A rose ketone fragrance compound identical to delta-damascone, restricted under EU Annex III/161 as a skin sensitizer.

Rose Ketone-3 is chemically identical to delta-damascone (both CAS 57378-68-4) and shares the same EU Annex III/161 restriction. This compound is used for its powerful rose-like odor in fragrance compositions. The EU restriction stems from documented skin sensitization potential, requiring concentration limits in cosmetic products. IFRA guidelines establish safe use levels for this and related damascone isomers.

Known concerns

  • EU Annex III/161 restriction as fragrance allergen
  • Skin sensitization potential
  • Concentration limits required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.