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Biotech actives

S-DNA APTAMER-1

70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

S-DNA Aptamer-1 is a synthetic short DNA fragment used in cosmetics for targeted skin signaling claims. It is generally non-irritating in formulations, but published evidence for visible benefit remains preliminary.

Function

ANTIOXIDANTBUFFERINGUV FILTER

Skin benefits

  • Biotech-derived oligonucleotide marketed for targeted skin signaling
  • Used at very low percentages with minimal residue
  • Hydrophilic, non-occlusive, generally non-irritating in formulas
  • Often paired with peptides for anti-aging positioning

Known concerns

  • Very limited independent peer-reviewed evidence for cosmetic efficacy
  • No specific SCCS opinion on cosmetic aptamers
  • Requires controlled preservation and supply chain
  • Marketing claims often exceed published data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.