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Antimicrobial

S-POLYBIA-MP-II

55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A 14-amino-acid synthetic peptide identical to a wasp venom toxin (Polybia-MP-II), used for antimicrobial and anti-sebum effects. Membrane-active venom peptides need careful dose control in cosmetics.

Function

ANTIMICROBIALANTI-SEBUM

Skin benefits

  • Antimicrobial peptide activity
  • Anti-sebum effects in oily skin
  • Synthesised — not extracted from venom

Known concerns

  • Identical sequence to a wasp venom toxin
  • Membrane-active peptides can lyse cells at high doses
  • Sparse independent safety data for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.