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Skin Conditioning

S-RNA

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic microRNA targeting the SIRT6 gene, designed for advanced anti-ageing cosmetics. Conceptually novel with limited long-term safety data and unsettled EU regulatory status — yellow with caution.

Skin benefits

  • Designed to target specific gene pathways
  • Used in advanced anti-ageing cosmetics
  • Theoretical mechanism for cellular renewal

Known concerns

  • Synthetic microRNA-class ingredient with limited long-term topical safety data
  • Potential off-target gene-silencing effects
  • Regulatory status uncertain in EU
  • Bioactivity dependent on delivery, stability and skin penetration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.