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Skin Conditioning

SACCHAROMYCES/PODOPHYLLUM PELTATUM FERMENT FILTRATE

CAS - Updated
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A yeast ferment of Mayapple, a plant containing the potent cytotoxin podophyllotoxin. The source plant is restricted in cosmetics — high-caution ingredient.

Skin benefits

  • Marketed for skin renewal effects
  • Yeast ferment processing may alter parent plant toxicity
  • Used at low concentrations in niche products

Known concerns

  • Podophyllum peltatum (Mayapple) contains podophyllotoxin — a potent cytotoxin/antimitotic
  • Topical podophyllotoxin causes severe skin irritation and systemic toxicity
  • Restricted in EU cosmetics; not appropriate for general use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.