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SESQUI-(DIHYDROXYPROPYL) GLYCINE

83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An amino acid derivative that acts like a gentle moisturizer and pH buffer — draws water in and helps keep skin balanced and comfortable.

Sesqui-(dihydroxypropyl) glycine is a mixed glycine derivative produced by the reaction of glycerin (glycerol) with glycine. 'Sesqui' indicates a 1.5:1 average substitution ratio, meaning it is a mixture of mono- and di-substituted products. The dihydroxypropyl groups enhance water-binding capacity compared to plain glycine, while glycine itself is a fundamental amino acid with excellent skin compatibility. Functions as a humectant and skin-conditioning agent.

Skin benefits

  • Strong humectant — attracts and binds water
  • Conditions and softens skin
  • Helps buffer and stabilize formulation pH

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.