Conditioning Agent
SH-DECAPEPTIDE-1 SR-PINEAPPLE STEM BROMELAIN
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic fusion peptide combining a decapeptide with pineapple stem bromelain enzyme, providing exfoliating and skin-conditioning benefits in cosmetic formulations.
sh-Decapeptide-1 sr-Pineapple Stem Bromelain is a synthetic fusion peptide produced by fermentation in E. coli, combining the gene sequences of sh-Decapeptide-1 and sr-Pineapple Stem Bromelain. The resulting peptide contains 222 amino acids. Bromelain is a well-characterized proteolytic enzyme mixture from pineapple stems (Ananas comosus) with documented exfoliating and anti-inflammatory properties. EU cosmetics regulation does not restrict bromelain itself, but proteolytic enzymes in cosmetic use require careful pH and concentration control to prevent over-exfoliation or irritation. The fusion format may moderate enzyme activity compared to free bromelain. No sensitization alert exists for the peptide portion.
Function
Skin benefits
- Bromelain component provides gentle enzymatic exfoliation of dead skin cells
- Fusion peptide format may offer targeted skin conditioning with reduced irritation vs. crude bromelain extract
Known concerns
- Proteolytic enzyme activity requires careful formulation control to prevent skin irritation from over-exfoliation
- Not recommended for use in combination with other exfoliating agents (AHA/BHA/enzymes)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.