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Skin Conditioning

SH-DSRNA-1

45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic double-stranded RNA designed for topical gene-silencing (RNAi) — a genuinely novel cosmetic technology. The borderline between cosmetic and pharmacological action and lack of SCCS review warrant caution.

Skin benefits

  • Targeted gene-silencing claim (RNAi)
  • Novel mechanism for cosmetic actives
  • Recombinant — no animal derivation

Known concerns

  • RNA-interference is a pharmacological mechanism — cosmetic appropriateness questioned
  • Novel ingredient — minimal independent safety data
  • Stability and penetration not well characterised
  • Possible off-target gene-silencing effects
  • SCCS has not reviewed this ingredient class

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Check your shelf

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.