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SH-DSRNA-2 HYDROXYPROPYL PEG-3 PROPYL CHOLESTERYLCARBAMATE

58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A novel biofunctional ingredient incorporating short hairpin double-stranded RNA (sh-dsRNA) linked to a PEG-modified cholesteryl carbamate, designed for advanced skincare targeting gene expression pathways.

This is a next-generation cosmetic ingredient leveraging RNA interference mechanisms. The sh-dsRNA component is designed to modulate gene expression in skin cells. The PEG-hydroxypropyl spacer improves solubility. Regulatory status in EU: not specifically restricted but requires full safety assessment under Regulation 1223/2009 as a novel bioingredient.

Skin benefits

  • Potential gene expression modulation for anti-aging
  • Innovative mechanism of action
  • Targeted skin response

Known concerns

  • Novel bioingredient requiring extensive safety data
  • RNA-based ingredients face regulatory scrutiny in EU
  • Potential for off-target gene effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.