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SH-DSRNA-3 HYDROXYPROPYL PEG-3 PROPYL CHOLESTERYLCARBAMATE

25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An experimental siRNA delivery system designed for targeted gene silencing in skin cells, with limited published safety data for cosmetic use.

This is a cholesterylcarbamate-modified PEG conjugate carrying short double-stranded RNA fragments (sh-dsRNA) for topical delivery. It falls outside established cosmetic ingredient lists and lacks the long-term safety profiling typical of cosmetic excipients. Regulatory submissions for novel genetic delivery systems require extensive evaluation not typical for cosmetic ingredients.

Known concerns

  • Experimental genetic delivery system
  • No established cosmetic safety history
  • May require biologic drug-level evaluation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.