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Antioxidant

SH-HEXAPEPTIDE-6 SP AMIDE

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A short, synthetic-human hexapeptide modelled on a PAR-2 receptor fragment, used as an antioxidant and signalling ingredient. Small peptides like this are typically very low-irritation and the EU has no restrictions on it.

Function

ANTIOXIDANT

Skin benefits

  • Short biomimetic hexapeptide derived from PAR-2 receptor sequence
  • Investigated for skin-soothing and anti-irritant signalling
  • Synthetic-human production with no animal-derived inputs

Known concerns

  • Cosmetic literature is limited compared to canonical signalling peptides
  • Stability dependent on packaging and pH
  • No EU regulatory restrictions identified

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.