Skin Conditioning
SH-OLIGOPEPTIDE-109 SP
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 32-amino-acid synthetic oligopeptide modeled on human Defensin-5, an innate-immunity peptide. Used for skin protection and conditioning; antimicrobial-leaning action. Limited but plausibly favorable safety profile.
Function
Skin benefits
- Modeled on human Defensin-5 — innate-immunity peptide
- Antimicrobial-leaning skin conditioning
- Synthetic — no animal sourcing
- Larger 32-residue peptide for targeted action
Known concerns
- Antimicrobial peptides can disrupt skin microbiome at high use levels
- Limited public efficacy data for this specific oligopeptide
- Skin penetration of 32-residue peptides is limited (acts surface-level)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.