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Skin Conditioning

SH-OLIGOPEPTIDE-109 SP

84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A 32-amino-acid synthetic oligopeptide modeled on human Defensin-5, an innate-immunity peptide. Used for skin protection and conditioning; antimicrobial-leaning action. Limited but plausibly favorable safety profile.

Function

SKIN PROTECTINGSKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Modeled on human Defensin-5 — innate-immunity peptide
  • Antimicrobial-leaning skin conditioning
  • Synthetic — no animal sourcing
  • Larger 32-residue peptide for targeted action

Known concerns

  • Antimicrobial peptides can disrupt skin microbiome at high use levels
  • Limited public efficacy data for this specific oligopeptide
  • Skin penetration of 32-residue peptides is limited (acts surface-level)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.