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(SH-OLIGOPEPTIDE-78 TRI (SH-PENTAPEPTIDE-22 SP)) PEPTIDES

86

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Synthetic signal peptides supporting skin matrix proteins like collagen and elastin, generally regarded as safe with no EU restrictions when properly purified and characterized.

(SH-Oligopeptide-78 Tri (sh-Pentapeptide-22 SP)) Peptides are synthetic signal peptides that stimulate the synthesis of skin matrix proteins including collagen, elastin, and fibronectin. They are not listed in EU restriction annexes. Peptides of this type have been used safely in cosmetic anti-aging formulations. The main safety considerations are purity (residual solvents, cleavage fragments) and sensitization potential which is generally low for synthetic signal peptides.

Skin benefits

  • Stimulates collagen synthesis for skin firmness
  • Promotes elastin production for skin elasticity
  • Supports overall skin matrix integrity
  • Anti-aging and skin repair benefits

Known concerns

  • Potential immune response with very large peptides
  • Purity and residual solvent concerns require quality control

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.