Conditioning Agent
SH-PENTAPEPTIDE-2
Safety score · 0–100
Excellent
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A short human-identical elastin-derived peptide that supports skin elasticity and conditioning through a simple glycine-proline-valine sequence.
SH-Pentapeptide-2 is a synthetically produced five-amino-acid human-identical peptide identical to a portion of human elastin, containing only glycine, proline, and valine. Such short, human-sequence peptides are among the safest cosmetic ingredients, with extensive use history and no EU restrictions in Annexes II through VI of Regulation (EC) No 1223/2009. Elastin-derived fragments at this size do not pose immunogenic risks and are well tolerated on skin.
Function
Skin benefits
- Skin elasticity support
- Skin conditioning
- Skin protecting
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.