Skip to content

Conditioning Agent

SH-POLYPEPTIDE-103

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A recombinant human heat shock protein — helps protect skin cells from stress and environmental damage.

sh-Polypeptide-103 is a recombinant human Heat Shock Protein beta-2 (HSPB2) produced in E. coli, containing up to 182 amino acids. Heat shock proteins are molecular chaperones that protect cells from thermal, oxidative, and UV stress. In cosmetics, it functions as a skin protectant. No GHS hazards, no EU restrictions. Used at trace concentrations for cellular stress defense.

Function

SKIN PROTECTING

Skin benefits

  • Cellular stress protection
  • Skin protecting
  • Anti-aging potential

Known concerns

  • Recombinant protein — limited topical efficacy data
  • Theoretical immunogenicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related conditioning agents

82
ACETYL HEXAPEPTIDE-68 AMIDE ACETATE
Conditioning Agent
 82
ACETYL SH-OLIGOPEPTIDE-30 SP
Conditioning Agent
 82
ACTINIDIA POLYGAMA LEAF/STEM EXTRACT
Conditioning Agent
 82
ANTENNARIA DIOICA CALLUS EXTRACT
Conditioning Agent
 82
BACILLUS FERMENT FILTRATE EXTRACT
Conditioning Agent
 82
BACILLUS/SEA SALT FERMENT FILTRATE
Conditioning Agent
 82
BUTYL HYDROXYCYCLOHEXANE CARBOXYLATE
Conditioning Agent
 82
BUTYROYL SH-PENTAPEPTIDE-12 SP
Conditioning Agent

Check your shelf

Find SH-POLYPEPTIDE-103 in your products.

Scan any cosmetic product with LuxSense to see if it contains SH-POLYPEPTIDE-103 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.