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Skin Conditioning

SH-POLYPEPTIDE-12

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A recombinant human peptide based on a portion of interleukin-4 (IL-4) used in skincare for barrier-support claims. Conservatively scored due to cytokine-mimetic class.

Function

SKIN CONDITIONING

Skin benefits

  • Recombinant human IL-4-derived peptide
  • Skin barrier-supporting potential
  • No skin penetration at peptide size

Known concerns

  • Cytokine-mimetic peptide — theoretical immunomodulation
  • Brand-proprietary efficacy data
  • Recombinant production residues at trace levels

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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ACETYL HEXAPEPTIDE-76 AMIDE
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.