Conditioning Agent
SH-POLYPEPTIDE-2 SR-EGYPTIAN SCORPION OLIGOPEPTIDE-1
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A scorpion-human fusion peptide combining venom and human sequences for skin protection, with moderate concern due to sensitizing potential.
A fusion peptide produced in E. coli combining Egyptian scorpion venom oligopeptide with human sh-Polypeptide-2. Scorpion venom-derived sequences carry a risk of sensitization and potential neurotoxic effects, placing this in the EU Annex III sensitizer range. Requires careful formulation and may not be suitable for sensitive skin. No specific EU restriction number assigned, but venom-derived peptides are subject to scrutiny under the Cosmetics Regulation.
Function
Skin benefits
- Skin protection
Known concerns
- Potential sensitizer (scorpion venom origin)
- Possible immunogenic response in sensitive individuals
- EU regulatory scrutiny for venom-derived peptides
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.