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Skin Conditioning

SH-POLYPEPTIDE-31

Updated
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A biosynthetic copy of human Insulin-Like Growth Factor 2, used for skin conditioning. Cautious tier because IGF-2 carries general growth-factor concerns despite minute cosmetic doses.

Function

SKIN CONDITIONING

Skin benefits

  • Biosynthetic IGF-2 analog for skin conditioning
  • High-purity E. coli production
  • Used at very low cosmetic doses

Known concerns

  • IGF-2 is an insulin-like growth factor — caution warranted
  • Theoretical concern for stimulating dormant lesions
  • Limited long-term cosmetic safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
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(ARNICA MONTANA/CALENDULA OFFICINALIS/MATRICARIA CHAMOMILLA) FLOWER EXTRACT
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(ARTEMISIA SIEVERSIANA/DIMOCARPUS LONGANA) FLOWER/LEAF/STEM EXTRACT
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 70
(ASPARAGUS COCHINCHINENSIS/LIRIOPE MUSCARI/REHMANNIA CHINENSIS) ROOT EXTRACT
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 70
(CNIDIUM OFFICINALE/COPTIS CHINENSIS/GLYCYRRHIZA URALENSIS) ROOT EXTRACT
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 70
(VETIVERIA ZIZANOIDES ROOT/PUERARIA THUNBERGIANA FLOWER/LEAF/STEM) WATER
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1,3-Dihydroxy-2-propanone
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 70
ABIES ALBA WOOD EXTRACT
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.