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SH-POLYPEPTIDE-50 SH-POLYPEPTIDE-56

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A long recombinant fusion peptide combining two synthetic human peptide sequences — designed to deliver combined conditioning and humectant benefits in skincare formulations.

sh-Polypeptide-50 sh-Polypeptide-56 is a recombinant fusion peptide produced in E. coli, formed by genetically fusing two synthetic human-derived peptide sequences. The fused peptide chain is 1790 amino acids long, making it relatively large for a cosmetic peptide. The full sequence consists of the 20 standard amino acids. Fusion peptides of this type are engineered to combine the properties of both parent sequences, potentially offering multiple skin conditioning benefits. No EU restrictions apply.

Function

SKIN CONDITIONING

Skin benefits

  • multi-functional skin conditioning
  • humectant hydration
  • skin barrier support

Known concerns

  • very large peptide may have limited skin penetration
  • E. coli expression requires endotoxin control

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.