Humectant
SH-POLYPEPTIDE-98 HEXAPEPTIDE-40
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A recombinant human peptide fusion grown in HeLa cells used as a humectant and skin conditioner. Generally low risk at cosmetic dilutions, but mammalian-cell production raises purification and sourcing questions.
Function
Skin benefits
- Humectant action attracts and binds water
- Skin conditioning via signaling-mimetic peptide
- Recombinant origin in mammalian cells matches human glycosylation
Known concerns
- HeLa-cell production raises sourcing/ethical questions for some users
- Limited public safety review
- Possible residual host-cell proteins if poorly purified
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related humectants
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.