Emollient
SILICA POLYSILSESQUIOXANE PROPYLDISULFIDEACETYL PENTAPEPTIDE-4
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A silica particle covalently linked via a disulfide bond to pentapeptide-4 — an emollient and humectant carrier system. Generally low-risk in leave-on use; particle-size and formulation specifics matter for silica safety.
Function
Skin benefits
- Combines emollient silica particle with skin-conditioning peptide
- Pentapeptide-4 has a long cosmetic-use track record
- Disulfide tether allows controlled peptide release
Known concerns
- Silica nanoparticle considerations depend on particle size
- Limited specific safety dossier for this conjugate
- Disulfide stability in formulation needs control
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related emollients
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.