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Humectant

SILKWORM R-SLEEPING CHIRONOMID POLYPEPTIDE-1/R-SLEEPING CHIRONOMID POLYPEPTIDE-2

73

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A peptide produced inside silkworms that have been engineered to express drought-tolerant midge proteins. It targets long-lasting hydration. Cosmetic safety data is thin, so it sits in the cautious-but-clean Yellow band.

Function

HUMECTANTSKIN CONDITIONING

Skin benefits

  • Skin-conditioning humectant function
  • Inspired by anhydrobiosis-tolerant chironomid proteins for moisture retention
  • Recombinant production reduces wild sourcing pressure

Known concerns

  • Silkworm-host expression may carry residual host proteins — low but non-zero allergy risk for sericin-sensitive users
  • Limited public toxicology dossier
  • Heterogeneity across manufacturers

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related humectants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.