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Skin Conditioning

SPERMIDINE

CAS 124-20-9
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A natural polyamine studied for cell longevity and skin renewal. Pure spermidine is corrosive, but cosmetics use trace levels where it is well tolerated.

Function

ANTIOXIDANTHAIR CONDITIONING

Skin benefits

  • Polyamine with autophagy-related antioxidant interest
  • Skin-conditioning at trace levels
  • Stable in aqueous formulas

Known concerns

  • Pure substance is corrosive (GHS H314) — finished cosmetics use trace levels
  • Limited topical safety data
  • Possible irritation if over-dosed

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.