Skin Conditioning
SPERMIDINE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A natural polyamine studied for cell longevity and skin renewal. Pure spermidine is corrosive, but cosmetics use trace levels where it is well tolerated.
Function
Skin benefits
- Polyamine with autophagy-related antioxidant interest
- Skin-conditioning at trace levels
- Stable in aqueous formulas
Known concerns
- Pure substance is corrosive (GHS H314) — finished cosmetics use trace levels
- Limited topical safety data
- Possible irritation if over-dosed
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.