TALC

45

Caution

CAS Number: 14807-96-6

About TALC

A mineral powder used in cosmetics for its silky feel and oil-absorbing properties — recently upgraded to 'probably carcinogenic' by WHO/IARC even without asbestos. Historically controversial due to asbestos contamination risk.

Detailed Analysis

Talc (hydrous magnesium silicate, Mg₃Si₄O₁₀(OH)₂, CAS 14807-96-6) is a naturally occurring mineral used as a texturiser, absorbent, and slip agent in cosmetics. EU Annex III/59 restricts its use (particle size specifications). IARC (2024) reclassified talc not containing asbestos as Group 2A ('probably carcinogenic to humans'), based on limited evidence for ovarian cancer, sufficient evidence in animals, and strong mechanistic evidence. Talc containing asbestos is Group 1 (carcinogenic). The geological proximity of talc and asbestos deposits creates ongoing contamination risk — the FDA withdrew its proposed standardised testing rule in 2025. The CIR Expert Panel reviewed talc and found it safe when free from asbestos and not used near the perineum.

Skin Benefits

  • Absorbs excess oil and moisture
  • Provides silky, smooth texture
  • Reduces shine and mattifies skin
  • Helps cosmetics glide smoothly on application

Known Concerns

  • IARC Group 2A — probably carcinogenic to humans (even asbestos-free)
  • Risk of asbestos contamination from natural mining proximity
  • Limited evidence linking perineal use to ovarian cancer
  • FDA withdrew standardised asbestos testing rule in 2025
  • Inhalation concerns for powdered products
  • EU restricted with particle size specifications

Safety Score

45

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

PubChem

National Library of Medicine compound data

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.