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Tefazoline (INN) and its salts

CAS 1082-56-0
6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Tefazoline (inn) And Its Salts is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Tefazoline is an alpha-adrenergic agonist with vasoconstrictive activity historically used as a nasal decongestant. It is prohibited in cosmetic products under EU Regulation (EC) No 1223/2009 Annex II (prohibited substances). The ingredient has no CosIng entry as a permitted cosmetic ingredient, and its pharmacological activity as a sympathomimetic vasoconstrictor is incompatible with cosmetic safety requirements.

Known concerns

  • Sympathomimetic vasoconstrictor — prohibited in cosmetics (EU Annex II)
  • No cosmetic safety assessment available
  • Potential cardiovascular and systemic effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.