Skin Conditioning
TETRACARBOXYMETHYL DIPEPTIDE-12
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A dipeptide with four carboxymethyl substitutions, used for skin conditioning. Mild short peptide; evidence base is supplier-driven.
Tetracarboxymethyl dipeptide-12 is a carboxymethylated variant of the same dipeptide backbone found in the hexa- and octa-substituted grades. The carboxymethyl groups boost water solubility and contribute mild chelation-like behavior. As a short peptide under 0.5% in finished products, the class is broadly well tolerated. There is no CIR or SCCS assessment for this specific grade, and efficacy support comes from supplier studies. Safety is reassuring by analogy to other short modified peptides rather than direct review.
Function
Skin benefits
- Skin-conditioning
- Soluble for aqueous serums
Known concerns
- No independent monograph
- Evidence primarily from supplier
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.