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TETRAHYDRO-6-NITROQUINOXALINE

28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Tetrahydro-6-nitroquinoxaline is a cosmetic ingredient used in product formulations. Note: subject to regulatory restrictions in some markets. Exercise caution due to limited available safety data.

Tetrahydro-6-nitroquinoxaline is a reduced quinoxaline derivative bearing a nitro substituent at the 6-position. Quinoxaline and its nitro-substituted derivatives are associated with mutagenic and carcinogenic potential via nitro-reduction to reactive oxygen species and DNA-adduct-forming intermediates. It is listed in EU Annex II/1240, prohibiting its use in cosmetic products in the EU. There are no approved cosmetic applications.

Known concerns

  • EU Annex II restricted (II/1240) - prohibited in EU cosmetic products
  • Nitro-reduction to mutagenic/carcinogenic intermediates
  • Potential DNA-adduct formation
  • No approved cosmetic applications

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.