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TETRAHYDRO-DIMETHYLNAPHTHYL-PROPAN-1-ONE

CAS 74499-60-8
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

TETRAHYDRO-DIMETHYLNAPHTHYL-PROPAN-1-ONE is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Tetrahydro-Dimethylnaphthyl-Propan-1-one is a tetralin (tetrahydronaphthalene) ketone with a propanone substituent. The saturated bicyclic ring system provides metabolic stability compared to unsaturated aromatic analogs. It is not listed in EU Annex II (banned substances) or Annex III (restricted substances) of the Cosmetics Regulation, suggesting permitted cosmetic use. The ketone functionality is adjacent to the tetralin ring (position 1), which may contribute to some reactivity, but the saturated nature of the ring system limits oxidative metabolism concerns.

Skin benefits

  • Provides amber, woody, tobacco-like fragrance notes
  • Acts as a fragrance fixative

Known concerns

  • Limited comprehensive skin safety data
  • Benzylic ketone position may undergo oxidation
  • Theoretical sensitization concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.