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Tetrahydrofuran

CAS 109-99-9
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Tetrahydrofuran is a cosmetic ingredient. Exercise caution due to limited available safety data.

Tetrahydrofuran (THF) is a cyclic ether solvent classified as a CMR Category 2 substance under EU CLP regulation, carrying H351 (suspected carcinogen), H361 (suspected reproductive toxicant), H370/H372 (organ toxicity), and H225 (highly flammable) statements. While it is primarily an industrial solvent, THF is restricted in cosmetic products due to its toxicity profile and safer alternative availability. It also carries H302, H336, H315, H332 statements indicating acute toxicity and irritation hazards.

Known concerns

  • Suspected carcinogen (H351)
  • Suspected reproductive toxicant (H361)
  • Organ toxicity (H370/H372)
  • Highly flammable (H225)
  • Acute toxicity (H302/H332)
  • CMR Category 2 substance

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.