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TETRAMETHYL-1-OXASPIRO-6-DECENE

CAS 36431-72-8
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

TETRAMETHYL-1-OXASPIRO-6-DECENE is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Tetramethyl-1-Oxaspiro-6-Decene is a spirocyclic ether/alkene with an oxygen incorporated into the spiro ring system. Spiro compounds often have unique odor profiles due to their three-dimensional structure. The tetramethyl substitution provides lipophilicity, and the spiro connection prevents planarity. It is not listed in EU Annex II (banned substances) or Annex III (restricted substances) of the Cosmetics Regulation. The spiro structure may confer resistance to metabolic oxidation.

Skin benefits

  • Provides unique, complex fragrance notes
  • Spiro structure may offer good odor substantivity

Known concerns

  • Limited comprehensive skin safety data
  • Spirocyclic structure may have unexpected metabolic fate
  • Minor theoretical skin irritation potential at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.