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TETRAMETHYL-HEXADECATETRAEN-3-OL

CAS 68931-30-6
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A long-chain polyunsaturated alcohol with skin irritation potential (H315) used as a fragrance ingredient at low concentrations.

This hexadecatetraenol is a 16-carbon chain with four double bonds and a terminal hydroxyl group (tetraenyl alcohol). The high degree of unsaturation (4 double bonds) creates significant reactivity and potential for oxidation products that may be allergenic. The H315 classification flags skin irritation potential. The polyene structure is reminiscent of certain natural skin lipids but also creates instability concerns. Use in cosmetic formulations requires antioxidant protection and low-temperature storage to prevent oxidation and allergen formation.

Skin benefits

  • Provides complex unsaturated fragrance note

Known concerns

  • H315 skin irritation
  • High unsaturation - oxidation and allergen formation risk
  • Requires antioxidant protection in formulations
  • Limited long-term sensitization data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.