Plant alkaloid (pharmaceutical)
TETRANDRINE
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Tetrandrine is a pharmacologically active alkaloid from Stephania tetrandra, with hepatotoxicity and pulmonary toxicity concerns. It is more drug than cosmetic and lacks regulatory approval for skin care.
Function
Skin benefits
- Bisbenzylisoquinoline alkaloid from Stephania tetrandra
- Studied for anti-inflammatory effects
- Calcium channel blocker activity
Known concerns
- Pharmacologically active alkaloid, not appropriate as a cosmetic
- Hepatotoxicity reported in oral use
- Pulmonary toxicity in animal studies
- Aristolochic acid contamination risk in source plants
- Not approved for cosmetic use by SCCS
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.