Synthetic cosmetic peptide
TETRAPEPTIDE-116
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Tetrapeptide-116 is a synthetic four-amino-acid peptide used as a skin conditioning active. Tetrapeptide-class actives are generally well tolerated but specific data on this peptide are limited.
Function
Skin benefits
- Short-chain peptide marketed for skin signaling and conditioning effects
- Cosmetic peptides generally support hydration, smoothness and barrier
- Synthetic peptides are vegan, non-animal and stable in many formulas
Known concerns
- No public CIR or SCCS dossier; safety based on the broader tetrapeptide class
- Efficacy and long-term safety data limited compared to better-known peptides
- Potential immunogenicity or allergy in rare individuals using novel peptides
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related synthetic cosmetic peptides
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.