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Skin Conditioning

TETRAPEPTIDE-124

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic four-amino-acid peptide marketed as a skin-conditioning signal peptide. Like most modern designer peptides, used at trace levels with limited public safety literature.

Tetrapeptide-124 is a chemically synthesized four-amino-acid peptide developed for cosmetic skin-conditioning applications. Designer peptides in this naming series are typically supplied as dilute solutions and used at parts-per-million concentrations in serums and creams. The class as a whole is considered low-irritation and low-systemic-risk because the peptide payload is small and unstable on the skin surface, but Tetrapeptide-124 itself does not yet have published CIR or SCCS reviews, and supplier-independent efficacy data is limited. INCI is listed in EU CosIng. Default tier: yellow with low evidence.

Function

SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Skin-conditioning signal peptide
  • Targets visible signs of aging at trace use levels
  • Compatible with most water-based formulas

Known concerns

  • Limited independent safety/efficacy data
  • No CIR or SCCS monograph yet
  • Real-world activity depends on stabilization system

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.