Skin Conditioning
TETRAPEPTIDE-124
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic four-amino-acid peptide marketed as a skin-conditioning signal peptide. Like most modern designer peptides, used at trace levels with limited public safety literature.
Tetrapeptide-124 is a chemically synthesized four-amino-acid peptide developed for cosmetic skin-conditioning applications. Designer peptides in this naming series are typically supplied as dilute solutions and used at parts-per-million concentrations in serums and creams. The class as a whole is considered low-irritation and low-systemic-risk because the peptide payload is small and unstable on the skin surface, but Tetrapeptide-124 itself does not yet have published CIR or SCCS reviews, and supplier-independent efficacy data is limited. INCI is listed in EU CosIng. Default tier: yellow with low evidence.
Function
Skin benefits
- Skin-conditioning signal peptide
- Targets visible signs of aging at trace use levels
- Compatible with most water-based formulas
Known concerns
- Limited independent safety/efficacy data
- No CIR or SCCS monograph yet
- Real-world activity depends on stabilization system
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.