Peptide/Active
TETRAPEPTIDE-44 NICOTINATE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A short peptide conjugated with a vitamin B3 (niacinamide) ester, marketed for anti-aging benefits in skincare. Peptides like this are generally well tolerated but evidence remains largely brand-driven.
Function
Skin benefits
- Combines a signal peptide with niacinamide delivery
- May support skin firmness and tone
- Targets visible signs of aging
- Low irritation potential typical of peptides
Known concerns
- Limited independent clinical evidence
- Novel ingredient with sparse formal safety review
- Efficacy claims often exceed supporting data
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related peptide/actives
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.