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Skin Conditioning

TETRAPEPTIDE-5

CAS - Updated
84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic tetrapeptide based on alanine, histidine and serine residues, used in skincare primarily for hydration and conditioning. Clean topical safety profile with no significant documented concerns at cosmetic use levels.

Skin benefits

  • Composed of common, well-tolerated amino acids
  • Used primarily for skin hydration and conditioning
  • Stable at typical skincare pH
  • Low irritation potential at cosmetic use levels

Known concerns

  • Limited independent efficacy data
  • Activity is supplier and concentration dependent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.