Skin Conditioning
THREONYL ORNITHINE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A small dipeptide made of threonine and ornithine. Gentle conditioning and hydration, with a clean safety profile typical of simple peptides.
Threonyl ornithine is a dipeptide composed of threonine and ornithine, two proteinogenic/non-proteinogenic amino acids both present in human skin and natural moisturizing factor. It functions as a skin conditioning agent and humectant. Small peptides like this have no CMR, genotox, or endocrine flags; they are not systemically absorbed at cosmetic concentrations. EU CosIng lists simple amino-acid peptides under skin conditioning. Efficacy data is modest but mechanistically plausible. Score at the entry of Good tier (80) — clean safety profile with moderate but coherent evidence.
Function
Skin benefits
- Amino-acid-based hydration
- Supports natural moisturizing factor
- Non-irritating peptide
- Gentle conditioning
Known concerns
- Modest independent efficacy data
- Peptide stability formulation-dependent
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.