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Skin Conditioning

THURFYLNICOTINATE HCL

CAS 221363-35-5 Updated
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nicotinic-acid ester that triggers temporary flushing and warmth, used in massage and sports rubs. The vasoactive effect borders on drug-like, so it sits at lower yellow.

Function

SKIN CONDITIONING

Skin benefits

  • Niacin (vitamin B3) ester
  • Vasodilation increases skin circulation
  • Used in massage and sports formulations
  • Long-standing cosmetic use

Known concerns

  • Causes flushing and warmth — not desired in everyday skincare
  • Possible irritation in sensitive skin
  • Drug-like vasoactivity blurs cosmetic-drug line
  • Avoid on broken skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.