TOCOPHERYL NICOTINATE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A vitamin E (tocopherol) derivative linked to nicotinic acid that combines antioxidant protection with improved skin penetration, used for anti-aging and skin-brightening formulations.
Tocopheryl Nicotinate (CAS 16676-75-8 and others) is the ester of d-alpha-tocopherol (natural vitamin E) with nicotinic acid. Unlike nicotinic acid itself, the nicotinate ester is gradually cleaved in skin to release both vitamin E and nicotinic acid, providing combined antioxidant and skin-circulation benefits. Vitamin E and its derivatives are not restricted in EU cosmetics. The nicotinate form is considered gentler than free nicotinic acid and does not cause the flushing associated with nicotinic acid supplements.
Skin benefits
- Antioxidant protection against free radicals
- Improves skin microcirculation
- Skin-brightening benefits
- Moisturising and anti-aging
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.