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Vitamin E and niacin ester

TOCOPHERYL NICOTINATE

CAS 16676-75-8 / 43119-47-7 / 51898-34-1 / 86362-36-9
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Tocopheryl nicotinate is a hybrid ester of vitamin E and nicotinic acid used as an antioxidant and skin conditioner. It offers combined benefits with generally good tolerance at cosmetic use levels.

Skin benefits

  • Combines vitamin E and niacin derived skin benefits
  • Antioxidant support against environmental stress
  • Improves microcirculation and skin tone
  • Skin conditioning emollient

Known concerns

  • Possible mild flushing in sensitive users
  • Stability requires protection from oxidation
  • Hydrolyses to nicotinic acid which can sting
  • Limited large scale clinical data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.