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Antioxidant

TOCOPHERYLOXYPROPYL TRISILOXANE

CAS -
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A silicone-modified vitamin E that delivers antioxidant tocopherol with silky silicone slip. Generally safe but has limited public safety data.

Tocopheryloxypropyl trisiloxane is a hybrid molecule combining alpha-tocopherol (vitamin E) with a low-molecular-weight trisiloxane via an oxypropyl linker. Designed to deliver antioxidant activity with the dry, silky aesthetics of silicones, it is used in serums, foundations, and hair products. Tocopherol-derived antioxidants are well-tolerated; the trisiloxane carrier is non-volatile, low-irritation, and not associated with systemic absorption. Independent toxicology data on this specific molecule are limited, and silicones broadly raise environmental persistence questions. No CMR or GHS hazards documented at cosmetic use levels.

Function

SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING

Skin benefits

  • Delivers vitamin E antioxidant activity
  • Imparts silky, dry-touch finish
  • Helps protect lipids from oxidation

Known concerns

  • Limited public toxicology data
  • Silicone environmental persistence
  • Sparse independent efficacy studies

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.