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Toluene-2,5-diamine Toluene-2,5-diamine sulphate

CAS 95-70-5 / 615-50-9
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Toluene-2,5-diamine Toluene-2,5-diamine Sulphate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Toluene-2,5-diamine (also called 2-methyl-1,4-benzenediamine) and its sulfate salt are oxidative hair dye intermediates. In the EU, p-phenylenediamine-type hair dye precursors are restricted under Regulation (EC) 1223/2009 Annex III with specific concentration limits. The ingredient carries 'Danger' classification for acute toxicity (H301), skin sensitisation (H317), and environmental hazard (H410). Safe use requires strict adherence to the SCCS-authorised restrictions and oxidative coupling conditions.

Skin benefits

  • Essential hair dye intermediate enabling permanent colour formation

Known concerns

  • Acute oral toxicity (H301) - classified as Dangerous
  • Strong skin sensitiser (H317) - risk of allergic contact dermatitis
  • Dermal toxicity (H312) and inhalation toxicity (H332)
  • Serious eye damage (H319)
  • Aquatic toxicity (H400, H410, H411)
  • EU Annex III restricted with mandatory coupling agent requirements

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.