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Toluidine sulphate (1:1)

CAS 540-25-0
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Toluidine sulphate (1:1) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Toluidine Sulphate (CAS 540-25-0) is the sulfuric acid salt of toluidine (methylaniline). Aromatic amines of this type have been subject to safety scrutiny due to structural alerts for sensitisation and potential genotoxicity. Toluidine itself has been reviewed by the EU Scientific Committee on Consumer Safety (SCCS) for use in cosmetic products. The substance is not specifically listed in EU Annex II (prohibited) but its safety profile requires careful evaluation. This salt form has limited cosmetic applications.

Known concerns

  • Potential sensitisation from aromatic amine structure
  • Structural alerts for genotoxicity
  • Requires careful safety evaluation
  • Limited cosmetic applicability

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.